Cursed since childhood, dentist Charlie Logan cannot find the right woman. Even worse, he learns that each of his ex-girlfriends finds true love with the man she meets after her relationship with him ends. Hearing of Charlie's reputation as a good-luck charm, women from all over line up for a quick tryst. But when Charlie meets the woman of his dreams, he must find a way to break the curse or risk losing her to the next man she meets.
The bitter fight for supremacy between the three most popular girls at North Gateway High takes an unexpected turn when their classmate, Tanner, is outed and becomes the school’s first openly gay student. The trio races to bag the big trend in fashion accessories, the Gay Best Friend, while Tanner must decide whether his skyrocketing popularity is more important than the friendships he is leaving behind.