Though a childhood bout with polio left him dependent on an iron lung, Mark O'Brien (John Hawkes) maintains a career as a journalist and poet. A writing assignment dealing with sex and the disabled piques Mark's curiosity, and he decides to investigate the possibility of experiencing sex himself. When his overtures toward a caregiver scare her away, he books an appointment with sex surrogate Cheryl Green (Helen Hunt) to lose his virginity.
All grown up in post-apocalyptic 2018, John Connor must lead the resistance of humans against the increasingly dominating militaristic robots. But when Marcus Wright appears, his existence confuses the mission as Connor tries to determine whether Wright has come from the future or the past -- and whether he's friend or foe.