Four interwoven stories that occur on Halloween: an everyday high school principal has a secret life as a serial killer; a college virgin might have just met the one guy for her; a group of teenagers pull a mean prank; a bitter old recluse receives an uninvited guest.
Medical student Ted Grey graduates at the top of his class and quickly joins an elite pathology program, whose top students invite him into their circle. There he uncovers a gruesome secret: They play a game in which one tries to commit the perfect, undetectable murder, then the others compete to determine the victim's cause of death.
On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.